Daily Multivitamin May Reduce CVD & Cancer Risk
Why you can trust Nutri Advanced Every article on our site is researched thoroughly by our team of highly qualified nutritionists. Find out more about our editorial process.
The latest results to be released from the long-term Physicians Health Study II have shown that a daily multivitamin may help to protect men from cardiovascular health problems.
Researchers from Brigham and Women’s Hospital (Boston), Karolinska Instituet (Stockholm), and Harvard T.H. Chan School of Public Health have now analysed data from 18,530 male physicians over the course of 20 years. Back in 2012, analysis of the data at that point found that daily multivitamin use may reduce the risk of cancer by 8%. Latest findings from the study were published recently in The Journal of Nutrition and showed long-term multivitamin use (over a 20 year time period) to be significantly associated with a lower risk of major cardiovascular disease (CVD). The researchers also found no evidence of any safety concerns from long-term multivitamin use.
The men were randomly assigned to receive a daily multivitamin or placebo. Results showed that there were no significant reductions in major cardiovascular events, heart attack, stroke, or death from cardiovascular disease. However they did find that multivitamin users, who had cardiovascular disease at the start of the study were significantly less likely (44% risk reduction) to die of a heart attack.
“The precise mechanisms through which long-term multivitamin use may be more strongly associated with CVD are unclear from observational studies and may reflect residual confounding by healthy behaviours. Alternatively, a longer period of time may be necessary for multivitamins to affect the long-term development of CVD.”
In terms of possible mechanisms of action, there are a number of reasons why daily vitamin and mineral supplementation may protect long term heart health including supporting healthy homocysteine metabolism (B vitamins and folic acid), protecting LDL (low density lipoproteins) from oxidative damage and reducing endothelial dysfunction.
Rautiainen S, et al. Multivitamin use and the risk of cardiovascular disease in men. The Journal of Nutrition. Published online ahead of print, doi: 10.3945/jn.115.227884
This website and its content is copyright of Nutri Advanced ©. All rights reserved. See our terms & conditions for more detail.
Nutri Advanced has a thorough researching process and for any references are included, each source is scrutinised beforehand. We aim to use the highest value source where possible, referencing peer-reviewed journals and official guidelines in the first instance before alternatives. You can learn more about how we ensure our content is accurate at time of publication on our editorial policy.
Most Popular Articles
Learn more about the different types of vitamin C, the different benefits you get from different types, and what you get for spending more on a good supplement.
In this research review article, we take a closer look at a lesser-known natural compound called myo-inositol that has been found to have significant potential to improve many of the prevalent features of PCOS.
Read the top 10 reasons that kids should have plenty of Omega-3- an essential fatty acid- including for depression, brain function, sleep & reading/maths skills.