Technical Papers

These fully referenced documents are aimed at health professionals and explain the in-depth aetiology of certain conditions and make referenced suggestions for how to overcome them.

NB: These documents are available to health professionals only.

  • How to Naturally Support the Menopausal Transition with Key Nutrients and Botanicals

    There’s widespread misconception that menopause and perimenopause are ‘disorders’ caused by falling hormone levels that need to be cured. In fact, perimenopause and menopause are natural parts of every woman’s health journey...

  • The Widespread Clinical Applications of Berberine

    For professional use only. 

    Berberine is a firm favourite among healthcare practitioners. It is best known for its anti-microbial activity against a range of pathogens including bacteria, fungi and protozoans, and is a primary herbal ingredient used to support the elimination of Small Intestinal Bacterial Overgrowth (SIBO).  More recently however, research has been prolific in identifying new benefits and clinical applications...

  • Supporting Small Intestinal Motility With Ginger, Artichoke & N-Acetyl-L-Carnitine

    Number 149. For professional use only. 

    Scientific interest in small intestinal bacterial overgrowth (SIBO) has increased significantly in recent years. Once unheard of, SIBO is now considered to be a commonly overlooked and underdiagnosed gastrointestinal health problem that may be a major underlying cause of Irritable Bowel Syndrome (IBS). In fact, many gastrointestinal experts now suggest that SIBO may be at the root of 50 - 85% of IBS cases.

  • 2'-Fucosyllactose (2'-FL) - The Crucial Role of a Natural Trisaccharide Found in Human Milk

    Number 148. For professional use only. 

    A vast myriad of interconnected elements must work in harmony to support optimal health. Research into two elements in particular - the gut microbiome and gut barrier function - is moving forward at an accelerated rate; and we now know just how crucial it is to nurture this delicate intestinal ecosystem as part of the bigger picture of health.

  • High Level Support for Pain, Inflammation and Joints

    Number 147. For Professional Use Only

    Arthritis is a leading cause of pain and disability worldwide. In the UK alone, more than 10 million people have arthritis, or similar conditions characterised by inflammation in the joints that causes pain, swelling and stiffness. There are different types of arthritis; the most common ones are osteoarthritis (OA)(a degenerative condition initially affecting the smooth cartilage lining of the joint) and rheumatoid arthritis...

  • Collagen and Supporting Nutrients for Joints and Bones

    Number 146. For Professional Use Only

    The musculoskeletal system provides form, support, stability and movement to the body. It includes the bones of the skeleton and the cartilages, ligaments and other connective tissue that stabilize or connect the bones, so it is vital that this important structure is supported.

  • Nutritional Support for Detoxification

    Number 145. For Professional Use Only

    Providing nutritional support for the body’s detoxification processes is fast gaining popularity all over the world. Today we recognise that although the body is designed to eliminate toxins, it cannot always handle the overload present in today’s environment. 

  • Using Combined Herbal Therapy to Eradicate Small Intestinal Bacterial Overgrowth (SIBO)

    Number 144. For Professional Use Only

    In this technical paper, we take a closer look at individual herbal extracts which have demonstrated significant antimicrobial activity and how these may be synergistically combined to naturally support the eradication of SIBO.

  • How to Protect your Brain's Complex Structure and Vital Functions Using Targeted Nutrients and Botanicals

    Number 143. For Professional Use Only

    Approximately 1 in 4 people in the UK will experience a mental health problem each year.1 and in England, 1 in 6 people report experiencing a common mental health problem (such as anxiety and depression) in any given week...

  • Supporting Optimal Liver Function: Vitamins, Minerals, Plant Extracts and Choline

    Number 142. For Professional Use Only

    The liver, found in the right upper abdomen, below the diaphragm, is one of the largest organs in the body. It is the most important organ of detoxification and continuously processes all forms of substances, from the digestive tract and rest of the body, throughout the day. 

  • Multi-Strain Probiotic Formulas

    Number 141. For professional use only.

    In 1992 a group of probiotic experts concluded that the optimal prophylactic culture is a mixed one: ‘Different strains can be targeted toward different ailments and can be blended into one preparation’1...

  • Supporting Joint Health with Curcumin, Ginger, Vitamin C & Vitamin D

    Number 140. For professional use only

    The history of curcumin goes back thousands of years, yet interest has rocketed recently, with more than 6000 articles published in the last two decades and over 65 clinical trials carried out on its use in chronic diseases...

  • Choosing a One-A-Day Multivitamin & Mineral Supplement

    Number 139. For professional use only

    It’s one of the most commonly asked questions - Do I need to take a daily multivitamin & mineral supplement? And the short answer is, yes; but make it a good one. In this technical paper, we’ll separate the facts from the fiction to help explain exactly why this is.

  • Liposomal Iodine - An Innovative Way to Optimise Thyroid Function

    Number 138. For Professional Use Only.

    Most people remember iodine from school science lessons - the brown solution that turned bright purple on contact with starch! Nowadays though, we know that its usefulness extends way beyond that…

  • Vitamin D3 and Vitamin K2: Partners in Bone Loss Prevention & Cardiovascular Protection

    Number 132. For Professional Use Only

    The role of vitamin D in bone protection is well established yet vitamin D remains one of the most widely studied vitamins with new research being published every day. This is because we are learning more about the inter-relationship of vitamin D with other nutrients and more about the exact mechanisms of action in the body. 

  • Nutrition and Eye Health

    Number 129. For professional use only

    About 2 million people in the UK regard themselves as having eye problems. Every day around 100 people start to lose their sight; as the population ages, this number may double within 25 years. Several nutrients have an integral role in maintaining the health of the eye; a great deal of interest has thus been generated...

  • Understanding The Natural Management of Pain and Inflammation

    Number 126. For Professional Use Only

    ABSTRACT: The primary reason why people seek the advice of health professionals is that they have some sort of pain. In the most general terms, pain is symptomatic of some form of dysfunction and resultant inflammatory processes in the body. In more specific terms, pain is the result of an injury to tissue either from physical trauma or from...

  • The Power of Papaya

    Number 125. For professional use only

    Papaya (or Carica papaya) is a member of the Caricaceae (Paw Paw) family and native to Central  America. The flesh, skin, seeds and stem of the papaya fruit have been used in traditional medicine for many years, for a variety of uses. In fact, the first ever written case of papaya being used for its healthful properties was in 1526. The Papaya plant is a rich source of...

  • Plant Sterols

    Number 123. For Professional Use Only

    Phytosterols are fats that are naturally present as minor components of various plant-derived foods, including vegetable oils, such as rapeseed and sunflower oil, and fruit, vegetables, grains, nuts and seeds. Although referred to as “plant fats”, they are chemically steroidal alcohols, and are structurally related to natural compounds produced by the body such as...

  • Depression: Natural Support with Eicosapentaenoic Acid (EPA)

    Number 122. For Professional Use Only

    Essential fatty acids (EFAs) are required for maintenance of optimal health but they cannot be synthesized by the body and must be obtained from dietary sources.1 Fish oils are a rich source of omega-3 polyunsaturated fatty acids (ω-3 PUFAs), in particular eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Low levels of ω-3 PUFAs have...

  • The Role of Detoxification in the Prevention of Chronic Degenerative Diseases

    Number 117. For professional use only

    ABSTRACT: The impact of environmental toxicity on health is startling; environmental exposure to toxic substances is suggested to cost billions in annual health dollars. Diseases that are linked directly to environmental exposure include many types of cancers and those syndromes characterised by fatigue, muscle weakness, and cognitive dysfunction...

  • Nutritional Strategies in the Prevention of Osteoporosis

    Number 116. For professional use only

    ABSTRACTOsteoporosis is a gradual reduction in bone mass that leads to an increased susceptibility to bone fractures. An estimated 1.5 million fractures are attributed to osteoporosis each year in the United States. With the rapid aging of the population, the suffering and healthcare costs associated with osteoporosis are steadily increasing. Experts agree...

  • Supporting Healthy Sleep

    Number 114. For Professional Use Only

    Sleep is a physical and mental resting state, a vital biological function, necessary for physical and emotional well-being. Insomnia, or sleeplessness, is a sleep disorder that affects significant numbers of our population, with the main symptoms being difficulty falling asleep, staying asleep and waking up too early every morning.1 Even just one night’s...

  • Gut Dysfunction and Chronic Disease: The Benefits of Applying the 5R® Programme

    Number 113. For professional use only

    ABSTRACT: Each day, the typical healthcare practice is challenged by several cases involving gastrointestinal (GI) complaints. Moreover, many conditions in which symptoms are not localized to the GI but may be systemic often involve an underlying GI dysfunction.

  • Nutritional Influences on Estrogen Metabolism

    Number 111. For professional use only

    ABSTRACTIt is now well known that one of the most prominent causes of breast cancer, as well as many other hormone related health problems in both men and women, is excessive estrogen exposure from both endogenous and exogenous sources. Improving estrogen metabolism can be of benefit in women with various conditions and family histories...

  • Natural Therapies for Osteoarthritis

    Number 110. For professional use only

    ABSTRACT: Osteoarthritis (OA) is the most prevalent form of arthritis, resulting in pain and motion limitation in over 20 million people in the U.S. Originating in joint cartilage, the disease is associated with degradation of the cartilage matrix and significant subchondral bone changes, triggering inflammation and pain of the surrounding joint and becoming...

  • Nutritional Support for the Three Phases of Care

    Number 101. For professional use only

    ABSTRACTNutritional support for the Three Phases of Care approach to injury recovery optimizes the biochemical pathways associated with the body’s healing process. Each phase of the healing process (acute, sub-acute, and chronic) can best be supported by therapeutic strategies that address the critical aspects of the phase. For example, during the...

  • Nutritional Support for Insulin Resistance

    Number 100. For professional use only

    ABSTRACT: The binding of insulin to its receptor in the cell membrane is the first step of a metabolic cascade leading to cellular glucose uptake. The term ‘insulin resistance’ refers to a reduced sensitivity of the cell to the action of insulin. When reduced insulin sensitivity exists, the body attempts to overcome the resistance by secreting increasing amounts of...

  • Nutritional Management of Stress-Induced Dysfunction

    Number 98. For professional use only

    In today’s fast-paced society the vast majority of individuals are under a constant barrage of stressors. These stressors are translated by the neuroendocrine system into signals that alter the body’s biochemistry to support a fight or flight response. While some of these changes may be beneficial in the short term (acute stress), they present an increased risk...

  • Nutrition in Babies & Young Children

    Number 95. For Professional Use Only

    The rate of growth in the first few years of a child’s life is phenomenal. In the first two years alone, a child will have doubled in height and probably trebled in weight. Mental, emotional and physical developments also take place at a similarly fast rate. It will come as no great surprise then that such a vast amount of growth means a high turnover of nutrients, which are...

  • The Benefits of Taking Hops for Phyto-Oestrogen Support

    Number 94. For Professional Use Only

    Soy has long been regarded as the best dietary source of phyto-oestrogens available, supplying generous quantities of the potent oestrogenic compound genistein. It seems now though that there may well be another plant source to take its place. Recent studies have now found 8-prenylnaringenin, the oestrogenic compound in hops, to be the most...

  • GI Friendly Joint Relief

    Number 83. For professional use only

    Arthritis is one of the most prevalent and debilitating diseases of modern times, with 1.75 million sufferers currently diagnosed with the condition in the UK,1 and many more left undiagnosed. Pharmaceutical anti-inflammatory drugs provide relief for many, but are accompanied by significant gastrointestinal side effects. Now, natural medicine can...

  • Rethinking Bone Strength : Nutritional Support for Osteoporosis

    Number 77. For professional use only

    As we get older, our bones tend to become less dense, making them brittle and vulnerable to fracture. This progressive loss of bone strength is known as osteoporosis, and particularly at risk are the hip, spine and wrist. Although the risk of becoming osteoporotic is tied to many dietary and lifestyle issues, the true cause of this condition remains somewhat unclear.

  • Sprains, Strains and Ligament Damage

    Number 75. For professional use only

    In today’s health-conscious society, sport and fitness play an important part in the daily lives of a growing number of people, and strenuous exercise is invariably accompanied by injury whether it be a muscle strain, an ankle sprain or a torn ligament. That’s why it is important to look after the health and well-being of your musculoskeletal system. Even minor physical...

  • Using Diindolylmethane to Modify the Metabolism of Oestrogens

    Number 72. For professional use only

    Long-term exposure to oestrogens, in the form of hormone replacement therapy or xenoestrogens, is associated with several health risks.1,2 The ratio of oestrogen metabolites (e.g. 2-hydroxyestrone over 16- hydroxyestrone) is an established indicator of hormonal balance in women and men, influencing the health of breast, endometrium, prostate and...

  • Supporting the Body with Glandular Extracts

    Number 71. For professional use only

    ABSTRACT: Up until recently organ meats remained an important part of human nutrition. Today, however, humans rarely consume them. Could this be why many people have low organ reserve and are prone to degenerative diseases and infections? Glandular therapy is said by many to be as important in optimising health and wellbeing as vitamins...

  • Complete Synergistic Support for an Underactive Thyroid Gland

    Number 70. For professional use only

    The thyroid gland is located at the base of the neck and produces thyroid hormones (T4 and T3), which are responsible for performing a multitude of activities in the human body. T4 is the least active of the thyroid hormones whilst T3 is the hormone that primarily regulates the metabolic rate within the cells. Even a small decline in the output of these hormones, if...

  • A Natural Method of Coping with Viral Infections

    Number 68. For Professional Use Only

    Viruses are all around us and can wreak havoc with our health. The ultimate goal of antiviral treatment is to restore function to the infected cell. However, this is usually difficult to achieve as viruses damage cells. Therefore, antiviral treatment aims to kill the virus and thus prevent its spread to other cells. This however, is not without its difficulties...

  • Glucosamine Sulphate

    Number 66. For professional use only

    Joint pain is a major challenge in society today. As we grown older, lifelong wear and tear on our joints begins to take its toll, causing destruction of the cartilage tissue, pain, inflammation and restricted joint mobility. Typically, analgesics and anti-inflammatory agents are used to help ease the pain of joint inflammation, but they do nothing to address the underlying...

  • Busy B Vitamins - Life’s Energy Givers

    Number 65. For professional use only

    B vitamins are commonly thought of as the vitality-giving nutrients. Essential for energy production, they are fundamental to good health. However, as a natural constituent of many wholefoods and whole-grain cereals, many people don’t get enough B vitamins from their diet. Foods are stripped of nutrients during the refining process, and so common...

  • The Secrets of Organic Sulphur

    Number 55. For Professional Use Only

    Sulphur has been around since the beginning of time. It is associated with pungent smells, active volcanoes and is referred to in ancient writings as brimstone. However, sulphur is also essential for life; so essential in fact that it is found in every cell of every living species.

  • Parasites: The Enemy Within

    Number 53. For Professional Use Only

    If you believe that parasitic infections are rare conditions only experienced by people living in under-developed countries with poor housing, sanitation and food sources – think again!

  • Dealing with the Problems of Elevated Homocysteine

    Number 45. For Professional Use Only

    Heart disease is the nation’s number one killer and we are all aware that high cholesterol is indeed a risk factor. However, many heart attack victims have cholesterol levels that would qualify as normal. So what else may be contributing to this frightening epidemic?

  • Star Flower Oil

    Number 44. For Professional Use Only

    Borage or starflower oil is extracted from the blue star shaped Borage flower. The active component of borage oil is an essential  fatty acid  Gamma Linolenic Acid (GLA). Borage oil is now thought to be a very superior source of GLA. Starflower oil contains 22% GLA. This is far higher than the amount of GLA found in Evening Primrose Oil.

  • Folate as 5-Methyltetrahydrofolate

    Number 36. For Professional Use Only

    Folate is an essential water-soluble B vitamin that cannot be made by the human body so dietary sources, food fortification and supplementation are needed to maintain normal levels. Folates are found in numerous foods of animal and plant origin but are especially abundant in dark green leafy vegetables specifically spinach, turnip greens, and broccoli. However...

  • Fighting Candida with Nutrition

    Number 32. For professional use only

    Candidiasis is an overgrowth of Candida albicans, a yeast-like fungus in the body. Candida albicans is a unicellular yeast found in everyone and is usually kept in check by the body’s good bacteria, namely Lactobacillus and Bifidus. If the immune system is compromised, the yeast can proliferate and transform into a pathogenic fungus that severely compromises the...

  • The Health Effects of Natural Stable Fish Oil

    Number 29. For professional use only

    Many people think that fat in the diet is bad. In fact, fat is necessary for life but most of us consume the wrong types of fat. Over the past century, our intake of different fats has changed markedly, with most of us eating far more saturated  fats and omega-6 fats from vegetable oils than ever before, whilst our intake of omega-3 fats from oily fish has decreased by...

  • Probiotics

    Number 22. For Professional Use Only

    Probiotics such as Lactobacillus and Bifidobacterium are microorganisms that inhabit the gut, supporting gut immunity and general gastrointestinal health. Probiotics have been used for many years to support a healthy balance of intestinal microflora. One of the primary considerations when buying a probiotic is to choose a strain that can establish itself and...

  • Chocamine® - Harnessing The Health Benefits of Cocoa Without Caffeine

    Number 18. For professional use only.

    The health benefits of cocoa have been demonstrated for many years. For over 3,000 years, chocolate has been highly prized like gold. It was around 2,000 BC that cocoa, or Theobroma cacao as it is officially termed, was said to have originated in the Amazon...

  • CoQ10

    Number 17. For Professional Use Only

    Coenzyme Q10 (CoQ10) is also called ubiquinone, a name that signifies its ubiquitous (widespread) distribution in the human body. CoQ10 is used by the body to transform food into adenosine triphosphate (ATP), the energy on which the body runs.

  • The Health Effects of Polyphenol Rich Superfoods

    Number 16. For Professional Use Only

    It’s a sad fact that very few people eat enough fruit & vegetables in their diet, with only 31% of adults aged 19 to 64, and 37% of adults aged 65 and over achieving the government recommended “5 a day”, according to the last published results of the National Diet and Nutrition Survey (NDNS). And now there is more and more evidence suggesting that actually, 5 a...

  • Dyspepsia: DGL Liquorice, Glycine and Supportive Botanicals

    Number 14. For Professional Use Only

    Dyspepsia is a term which encompasses a group of symptoms that come from a problem in your upper gastrointestinal tract, and causes include duodenal ulcer, stomach ulcer, oesophagitis (inflamed oesophagus), and gastritis (inflamed stomach). If no known cause can be found, if there are no clinically identifiable, structural gastrointestinal lesions, it is known...

  • Unravelling the Mystery of Chronic Fatigue Syndrome

    Number 13. For professional use only

    Fatigue is an incredibly common symptom of ill health; up to 30% of patients complain to their doctors of symptoms of fatigue, with a wide variety of possible causes. Chronic Fatigue Syndrome (CFS), formerly known as Myalgic Encephalomyelitis (ME) is a much rarer condition and describes a health problem where levels of fatigue are often so...

  • Curcumin

    Number 11. For Professional Use Only

    Interest in curcumin has gained considerable momentum over the last few years. Once best known as a constituent of the popular spice turmeric, curcumin is now fast becoming known for the many potential health benefits it has to offer. Turmeric is a popular spice used traditionally in South Asian and Middle Eastern cooking immediately...

  • Natural Support for a Healthy Prostate

    Number 10. For professional use only

    Over 30 million men suffer from prostate conditions that negatively affect their quality of life, yet most men aren’t aware of what their prostate is, or what it does. The prostate gland is a small gland that surrounds the urethra, a tube that transports urine from the bladder to the penis and carries semen during ejaculation. The prostate also produces a...

  • Chromium, Cinnamon and Alpha Lipoic Acid

    Number 09. For Professional Use Only

    The term ‘blood sugar level’ refers to the concentration of glucose in the blood at any given point. This level changes throughout the day and night depending on a range of variables such as diet, level of activity and lifestyle factors such as stress. It is important for optimal health that the blood sugar level doesn’t become too high or too low, therefore the body has an...

  • Serratiopeptidase

    Number 08. For professional use only

    Inflammation lies at the root of many common chronic health problems, from eczema, osteoarthritis and allergies to auto-immune conditions such as ulcerative colitis and rheumatoid arthritis. The very word ‘inflammation’ typically conjures up images of redness, pain and discomfort, and so is often viewed as something that needs to be completely eradicated from...

  • Immune Support: Beta 1-3/1-6 Glucans with Vitamins & Zinc

    Number 06. For Professional Use Only

    The immune system is one of the most complex systems in the human body; an intelligent and dynamic network of cells, tissues and organs that work together to defend the human body against foreign invaders such as bacteria, viruses, parasites and fungi. The immune system can be easily separated into two parts...

  • Natural Eggshell Membrane (NEM®)

    Number 05. For professional use only

    Natural Eggshell Membrane (NEM®) is a new source of natural glucosamine, collagen and chondroitin that has been scientifically studied and proven to have clinical effects for osteoarthritis. Doses of just 500 mg of NEM® daily have produced very rapid clinical effects in people with joint pain, muscle pain and osteoarthritis with evidence of significant benefit...

  • Branch-Chain Amino Acids (BCAAs)

    Number 04. For Professional Use Only

    The amino acids leucine, isoleucine and valine possess a similar branched-chain structure and are therefore referred to as branched-chain amino acids (BCAA). BCAAs account for 14–18% of the total amino acids in muscle proteins, are essential for muscle protein synthesis and play important roles in muscle metabolism and repair. Exercise is known to...

  • Leaky Gut: Glutamine, Live Bacteria with Vitamins, Minerals & Phytonutrients

    Number 03. For Professional Use Only

    The intestinal mucosa is an important protective barrier from potentially harmful gut contents, such as allergens and endotoxins. In intestinal permeability (IP) however, the passage of these noxious agents into the bloodstream increases and is associated with dysfunction and disease. A combination of Glutamine, live bacteria with Vitamins, Minerals...

  • Stress: Milk Protein Hydrolysate and Theanine

    Number 01. For professional use only

    Stress related illness is one of the leading causes of ill health and poor quality of life. Milk Protein Hydrolysate and Theanine are two unique nutrients for the management of stress related illness, in particular symptoms of anxiety.